Every year, 50 million people develop sepsis and 11 million people die. Sepsis is a life-threatening response to infection. It can be caused by any type of infection. It may lead to shock, multiple organ failure, and death, especially if not recognized early and treated quickly.
The number of sepsis cases is increasing dramatically. The Global Sepsis Alliance reports that hospitalizations for sepsis have doubled over the last 10 years. And while most associate sepsis with hospital infections, international surveys estimate that 20-40% of sepsis patients develop sepsis outside hospitals.
The effects of COVID-19 on the respiratory system are well-known, however, virtually all other organ systems can also be affected.The Global Sepsis Alliancehas concluded definitively that COVID-19 can cause sepsis.
大约8-10天后，大约2-5％的Covid-19患者中，大约2-5％发生了败血症的多器官损伤迹象。许多受Covid-19的患者将死于败血症及其并发症。现在，识别败血症的早期迹象并启动治疗至关重要。
people develop sepsis every year
people die
出院败血症
Sepsis is often diagnosed too late, because the clinical symptoms used for sepsis diagnosis like raised temperature, increased pulse or breathing rate, or white blood cell count are unspecific. In children, the signs and symptoms may be subtle and deterioration can be rapid.
即使是轻微的感染也会导致败血症。败血症是一种常见，但处于公认状态。这是由于对患者和医疗保健提供者中败血症的迹象的困惑，缺乏败血症的文献作为死亡原因，诊断工具不足以及不一致的标准临床指南治疗败血症。
Fever, shivering, very cold
Short of breath
Clammy or sweaty skin
极端疼痛
混乱或精神状况改变
Pale or discolored skin
Regardless of the setting, pre-hospital or hospital, the critical factor in patient survival is time—time to recognition and time to treatment. The risk of death from sepsis increases by as much as 8% for every hour that treatment is delayed.
败血症可能很难诊断，因为它具有与其他疾病的快速发作和重叠的症状。没有单一的败血症测试，因此学会识别和治疗败血症很关键。败血症的常见迹象包括发烧，发抖，极端疼痛，苍白或变色的皮肤，嗜睡，混乱或精神状态改变，呼吸急促以及缺乏排尿。
通过快速诊断和治疗，可以预防多达80％的败血症死亡。快速开始简单，及时的干预措施，包括静脉输液和靶向治疗以恢复循环，可以降低死亡的风险。早期败血症治疗不仅可以提高患者的安全性，而且具有成本效益，减少了医院和患者的重症监护床。
Simulation training can enable healthcare providers to accurately diagnose and treat sepsis. Using simulation scenarios to learn to identify standard and severe sepsis, to recognize sepsis in high-risk patients, to differentiate between sepsis and other conditions, and to assess and treat septic shock are among some of the learning objectives for simulation training.
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